Features of Metabolic Changes in Hypoxic Lesions of the Central Nervous System in Newborns

Tukhtaeva Mashkhura  Mukhiddinovna

Tukhtaeva Mashkhura Mukhiddinovna Assistant of the Department of Pediatrics No. 1 and Neonatology Samarkand State Medical Institute. Samarkand, Uzbekistan

Keywords: metabolism, hypoxic damage to the central nervous system, newborns

Abstract

The neonatal period and the first year of a child's life are characterized by the most active period of brain maturation, and the action of such an aggressive factor as hypoxia on the developing brain of a child dictates the need for further study of this pathology. The most significant changes in the statistical indicators of mortality and morbidity were noted among premature babies. The high frequency of severe combined perinatal pathology in this category of children led to an increase in childhood disability, in the structure of which the leading positions (21.2%) belong to the pathology of the nervous system and sensory organs. Among the etiological factors that are most significant in the pathogenesis of perinatal cerebral injuries, the leading role belongs to hypoxia. Literary analysis showed the relevance of this problem, which served as the purpose of the distribution. The aim of the study was to establish the nature of clinical and instrumental, psychomotor and metabolic changes in hypoxic lesions of the central nervous system in newborns. We observed 60 newborns with a gestational age of 28 to 41 weeks with hypoxic lesions of the central nervous system of the early period.

References

1. AleksandrovaV.A.Perinatal lesions of the central nervous system and their consequences in the practice of a pediatrician: a manual for doctors Alexandrova, E.A. Bratova.- SPb., 2008.- 70 p.
2. AlbitskyV.Yu. Mortality of adolescents in the Russian Federation / V.Yu. Albitsky, A.E. Ivanova, A.G. Ilyin et al. // Russian Pediatric Journal. -2009.-№3. - P.4-10.
3. Amasyants R.A. Clinic of Intellectual Disabilities: Textbook / R.A. Amasyants E.A. Amasyants.-Moscow: PedagogicalSocietyofRussia, 2009.- 320s
4. Afonin A.A. Dynamics of indicators of cerebral hemodynamics and endothelium of dependent factors of its regulation in children with perinatal CNS damage in the first year. Afonin, V.V. Strogulin, I. G. Loginova, N.A. et al. // Pediatrics - 2011. - T. 90. - No. 1. - p. 30-33.
5. A. A. Baranov The state of health of children in the Russian Federation // A.A. Baranov // Pediatrics. -2012.-T. 91.-No. 3.- S. 9-14.
6. T.V. Belousova Features of rehabilitation and therapy in the acute period of perinatal cerebral pathology / T.V. Belousova, L.A. Ryazhina // Journal of Neurology and Psychiatry. S.S. Korsakov. - 2010.-№11. S. 15-20.
7. Blinov D.V. Modern approaches to the pathogenesis and prognosis of the outcomes of hypoxic-ischemic lesions of the central nervous system in the perinatal period / D.V. Blinov // Obstetrics, gynecology and reproduction. - 2012.-T.6.-No.3.-P.34-38.
8. A. B. Palchik Hypoxic-ischemic encephalopathy newborns // A.B. Palchik, N.P. Shabalov. - SPb, 2010.- 510 p.