Morphological Changes of the Stomach in Chronic Gastritis

Bakhshillaeva Farogat  Namozovna; Mirsharopov U. M.

Bakhshillaeva Farogat Namozovna Post-graduate student of the Tashkent Medical Academy
Mirsharopov U. M. Scientific adviser: Doctor of Medical Sciences, Professor

Keywords: atrophic gastritis, rats, stomach, morphology

Abstract

In the work, 80 outbred white outbred rats of four months of age, weighing 170-200 g of the gastric mucosa with experimental gastritis, were studied. Animals were taken out of the experiment at 30 days of age by instantaneous decapitation of animals under ether anesthesia. After opening the abdominal cavity, microscopic changes in the stomach were examined.

Morphological studies of stomach tissues were performed under a Lake microscope. In the control groups of rats, the total thickness of the stomach wall in its cardia and at the junction with the duodenum remained unchanged; the mucosa and submucosa were well developed. In the second group of animals, when using non-steroidal anti-inflammatory drugs, dystrophic changes, desquamation of the mucous membrane prevailed, in some places hemorrhage and plethora of blood vessels, and the number of glandular structures began to decrease.

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