Modern Approaches to Treatment of Chronic Giardiasis

Abstract

This paper presents patients were examined according to a single scheme, which included a set of clinical and laboratory studies, a survey and examination of the patient. Clinical manifestations of the disease were assessed before the start of treatment, on the 5th day of therapy and immediately after the end of the course of treatment. The study group included 300 patients, including 197 aged 18 to 45 years (Group 1) and 103 children aged 5 to 18 years (Group 2). An analysis of clinical and anamnestic features showed that the leading symptoms in patients with giardiasis were lesions of the gastrointestinal tract in 65.9% of cases in adults and in 39.8% of cases in children. In second place are violations of the general condition in the form of asthenovegetative syndrome: in 58.4% of cases in adults and in 66.0% in children. In third place in terms of importance was identified toxic-allergic syndrome: in 42.6% of cases in adults and in 78.6% of cases in children. The observed patients in this group received traditional treatment with antiparasitic drugs. According to the coprological study of treated patients, re-isolation of Giardia cysts was noted: in adult patients - 62.4%, and in children - 65%. The effectiveness of treatment in adult patients is 37.6%, and in children - 35.0%.