The Role of Troponin And Il-6 in Immunological Assessment of Sarcopenia in Oncological Patients

Shakhnoza Shavkatovna  Shakhanova; Nodir Makhammatkulovich Rakhimov

doi:10.17605/cajmns.v6i3.2826

Shakhnoza Shavkatovna Shakhanova Department of Oncology, Samarkand State Medical University, Uzbekistan
Nodir Makhammatkulovich Rakhimov Department of Oncology, Samarkand State Medical University, Uzbekistan

DOI: https://doi.org/10.17605/cajmns.v6i3.2826

Keywords: Sarcopenia, Troponin, Interleukin-6, Biomarkers, Aging, Immunology

Abstract

Sarcopenia is a progressive syndrome associated with aging, leading to decreased muscle mass and function. This study aims to evaluate troponin and IL-6 as immunological biomarkers in sarcopenia. Methods: 180 patients aged 65–86 were analyzed for serum troponin T and IL-6 levels. Statistical analyses included Mann–Whitney U and logistic regression. Troponin was significantly elevated in sarcopenic patients. IL-6 showed a non-significant upward trend. Troponin was identified as an independent predictor. Troponin and IL-6 may serve as useful clinical biomarkers for sarcopenia. Troponin, in particular, holds promise for early detection.

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