Impact of Type 2 Diabetes on Men's Testosterone, BMI, and Lipid Profiles

Rawaa Ali  Rahmat

Rawaa Ali Rahmat Department Oral Pathology, College of Dentist, Mustansiriyah University, Bagdad, Iraq

Keywords: Type 2 Diabetes, Diabetes Mellitus, Testosterone, Body mass index, FBG, HBA1C

Abstract

Type 2 diabetes mellitus (T2DM) is the most prevalent type of diabetes globally, with well-understood pathophysiology. Recent research suggests testosterone may influence metabolic disorders like T2DM. This study aimed to examine the association between lipid profiles, testosterone levels, and body mass index (BMI) in 60 male Iraqi patients aged 40-50 with T2DM. A case-control study was conducted, including 60 diabetic men divided into two subgroups based on testosterone levels and a control group of 20 non-diabetic men. Measurements included testosterone, fasting blood glucose (FBG), HbA1c, lipid profiles, and BMI. Results indicated that diabetic men with low testosterone had significantly higher lipid profiles (TC, triglycerides, LDL, VLDL, HDL) and BMI compared to those with normal testosterone and the control group. FBG correlated positively with triglycerides and VLDL but negatively with HDL in the low testosterone group. Additionally, HbA1c negatively correlated with LDL, and the duration of diabetes correlated positively with cholesterol and LDL. The study concludes that low testosterone levels are common in T2DM patients and are associated with adverse lipid profiles and increased BMI, suggesting a potential role of androgens in lipid metabolism in diabetic patients.

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