Clinical and Morphological Features of Uterine Fibroid
Keywords:
uterine fibroid, leyomyoma, endometrial hyperplasia, myomectomy, hysterectomy.
Abstract
Uterine fibroid (UF) remains the most common benign tumor in gynecology. The aim of the study was to investigate the clinical and morphological features of uterine fibroid in women with surgical management tactics. We examined 53 women with symptomatic UF and 48 conditionally healthy women of reproductive and perimenopausal age admitted to the Multidisciplinary Clinic of the Tashkent Medical Academy (2020-2021yy). All women underwent standardized studies according to the National Protocol. Clinical and morphological analysis of women with surgical treatment tactics showed that leyomyoma prevails in histological examination of fibroid nodes, and simple typical endometrial hyperplasia on the background of endometritis in scraping morphology
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Bhat A.Sh. et al. Importance of Fibrosis in the Pathogenesis of Uterine Leiomyoma and the Promising Anti‑fibrotic Effects of Dipeptidyl Peptidase‑4 and Fibroblast Activation Protein Inhibitors in the Treatment of Uterine Leiomyoma. Reproductive Sciences. 10 August 2022. https://doi.org/10.1007/s43032-022-01064-0
Dobrokhotova Yu.E., Ibragimova D.M., Saprykina L.V. Myoma of the uterus // Guide for doctors, "GEOTAR - Media". - Moscow. - 2018 - P. 10-13.
Dubuisson, J. The current place of mini-invasive surgery in uterine leiomyoma management, J. Gynecol.Obstet. Hum. Reprod., 2019, vol. 48, pp. 77—81. https://doi.org/10.1016/j.jogoh.2018.10.004.
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Irnazarova D.Kh., Yuldasheva D.Yu., Najmutdinova D.K., Kayumova D.T., Sadikova D.R., Atahodjayeva F.A., Ahmedova G. Vitamin D status in women with uterine fibroids (UF) of the uzbek population. Journal of Critical Reviews. ISSN- 2394-5125 VOL 7, ISSUE 17, June 2020. Р. 2240-2250. http://www.jcreview.com/?mno=96009.
Irnazarova D.Kh., Yuldasheva D.Yu., Najmutdinova D.K., Kayumova D.T., Sadikova D.R., Atahodjayeva F.A., Ahmedova G. Effect Of Excess Body Weight And Deficiency Of Vitamin D On The Clinical Course Of Uterine Fibroid. European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3317-3329. https://ejmcm.com/article_4197.html
Jacqueline A. Piekos et al. Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid. Human Genetics (2022) 141:1739–1748. https://doi.org/10.1007/s00439-022-02442-z
Jeng C.-J., Ou K.-Y., Long C.-Y., Chuang L., Ker C.-R. 500 Cases of High-intensity Focused Ultrasound (HIFU) Ablated Uterine Fibroids and Adenomyosis // Taiwanese Journal of Obstetrics & Gynecology. – 2020. – №59 – Р. 865-871. https://doi.org/10.1016/j.tjog.2020.09.013.
Kudrina E.A., Baburin D.V. Uterine myoma: modern aspects of pathogenesis and treatment // Archives of Obstetrics and Gynecology. V.F. Snegirev. - 2016. - P. 4-11. DOI 10.18821/2313-8726-2016-3-1-4-10.
Myoma of the uterus // Clinical recommendations. ROAG. Moscow. - 2021. - P. 5-7.
Philip M.R. et al. Uterine leiofibroids revisited with review of literature // Abdominal Radiology (2021) 46:4908–4926. https://doi.org/10.1007/s00261-021-03126-4.
Podzolkova E.E., Korenaya V.V., Koloda Y.A. Uterine myoma // Guide for doctors. "GEOTAR-Media. - Moscow. - 2015. - P. 17-19.
RCOG. Green-top Guideline №67. – 2016. – P.2.
Shtykalova S. V.et al. Molecular Genetic Basis and Prospects of Gene Therapy of Uterine Leiomyoma. ISSN 1022-7954, Russian Journal of Genetics, 2021, Vol. 57, No. 9, pp. 1002–1016. DOI: 10.1134/S1022795421090118
Standards of diagnostics and treatment of gynecologic diseases in medical institutions of the health care system of RUz // MHRIUz. -2017. - pp.23, 79-80.
Tatarchuk T.F., Kosey N.V. New in hormonal regulation of uterine myoma development // Medical Aspects of Women's Health. - 2015. - № 7 (93). - С. 21-27.
WHO Guideline on Self-Care Interventions for Health and Well-Being. ISBN 978-92-4-003090-9. 13 July 2021. P.14. https://www.who.int/publications/i/item/9789240030909.
Williams A.R.W. Uterine fibroids – What’s new? // F1000Research. – 2017. – №6: 2109-2116. doi: 10.12688/f1000research.12172.1.
Published
2023-12-31
How to Cite
Irnazarova Dinara Khamidiloyevna, Yuldasheva Dilchekhra Yusupkhonovna, Irnazarov Akmal Abdullayevich, Gadayeva Dilshoda Abdigaffarovna, & Akhmedova Gulmira Amanovana. (2023). Clinical and Morphological Features of Uterine Fibroid. Central Asian Journal of Medical and Natural Science, 4(6), 1435-1441. Retrieved from https://www.cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/2249
Section
Articles
