Clinical and Functional State of the Kidneys in Middle-Age Patients with Arterial Hypertension
Keywords:
arterial hypertension, nephropathy
Abstract
Purpose of the study– assessment of the functional state of the kidneys and the formation of chronic kidney disease in middle-aged patients with arterial hypertension without associated diseases. Material and methods. 58 patients aged 38 to 60 years with a diagnosis of arterial hypertension were examined. A clinical diagnostic examination was carried out in the hospital: examination and history taking, biochemical blood test, general urine test, determination of glomerular filtration rate, monitoring of the clinical condition and tests during the hospital stay after 3 and 6 months. The study did not include patients with associated diseases or severe diseases of internal organs. Results and its discussion. In patients with arterial hypertension and without associated cardiovascular diseases, the main factors influencing the formation of renal dysfunction, manifested by hyposthenuria, albuminuria and proteinuria, are smoking, obesity, dyslipidemia and arterial hypertension. When arterial hypertension lasted more than 10 years, hypertensive nephropathy and chronic kidney disease were diagnosed in 67% of cases. Сonclusions. The results of the study confirm that smoking, obesity, dyslipidemia and arterial hypertension influence the formation of kidney dysfunction, manifested by albuminuria/proteinuria. The risk of developing hypertensive nephropathy with a duration of arterial hypertension of more than 10 years is 13 times higher than the risk of developing renal dysfunction with a duration of arterial hypertension of less than 5 years (RR=13.3, CI 95% 1.92–92.61;p<0.001). Nephroprotective antihypertensive therapy promotes reverse regression of albuminuria.
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2. 2013 ESH/ESC: guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) // Eur. Heart J. – 2013. – Vol. 34. – P.2159–219.
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7. Hypertension prevalence, awareness, treatment, and control in 115 rural and urban communities involving 47 000 people from China / W. Li, H. Gu, K. Teo [et al.] // J. Hypertens. – 2016. – Vol. 34. – P.39–46.
8. Orziqulova Shaxlo Chronic obstructive pulmonary disease and the metabolic syndrome: the state of the problem // ISSN: 2249-7137 Vol. 11, Issue 6, June, 2021 Impact Factor: SJIF 2021 = 7.492 ACADEMICIA:. ppt-305-311
9. Orziqulova Sh. A. Тhickness of epicardial adipose tissue as a predictor of Cardiovascular risk; Academicia a n i n t e r n a t i o n a l m u l t i d i s c i p l i n a r y r e s e a r c h j o u r n a l / ISSN: 2249-7137 Vol. 11, Issue 9, September 2021 Impact Factor: SJIF 2021 = 7.492 ppt 73-78
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11. Sh. A. Orzikulova Obesity and the Cardiovascular System// Research journal of trauma and disability studies// Volume: 01 Issue: 05 | 2021 ISSN: XXXX-XXXX www.academiczone.net ppt 9-16
12. Yakhyoyeva H.Sh*; Rizaeva M.A** Analysis and assessment of anthropometric body mass Index for women of fertilized age in bukhara region / academician A n i n t e r n a t i o n a l M u l t i d i s c i p l i n a r y R e s e a r c h j o u r n a l// ISSN: 2249-7137 Vol. 11, Issue 9, September 2021 Impact Factor: SJIF 2021 = 7.492// ppt 44-46
13. Yaxyayeva Hilola Sharifovna. Thyroid Cancer Diagnostics, Classification, Staging/ VOL. 1 NO. 5 (2021): JOURNAL OF INNOVATIONS IN SOCIAL SCIENCES/PPT 63-69
14. Хилола Шарифовна Яхъяева/COVID-19 И ЩИТОВИДНАЯ ЖЕЛЕЗА (ОБЗОР ЛИТЕРАТУРЫ)/ Research journal of trauma and disability studies// Volume: 01 Issue: 05 | 2021 ISSN: XXXX-XXXX // ppt 2-8.
15. Rizayeva Mekhriban Ahmadovna. Disorders of Carbohydrate Metabolism Overweight and Obesity (Innovations in Social Sciences Volume: 01 Issue: 01 | 2021ISSN: 2181-2594 ppt 90-98
16. Tursunova D .E. FEATURES OF THE SORPTION METHOD APPLICATION IN THE CORRECTION OF DYSLIPIDEMIA AND HYPERGLYCEMIA IN DIABETES MELLITUS/ Journal of Innovations in Social Sciences Volume: 01 Issue: 04 | 2021 ISSN: XXXX-XXXX // ppt 66-70
17. Rizayeva Mekhriban Ahmadovna. Metabolic Syndrome in Older Women / Volume: 01 Issue: 05 | 2021 ISSN: XXXX-XXXX www.academiczone.net ppt 24-28
18. Ш.М.Ахмедова, Д.Б.Рахматова. ПОДАГРИКНЕФРОПАТИЯГА ЗАМОНАВИЙ ҚАРАШЛАР // Доктор ахборотномаси №3.1 (96)—2020/стр 118-121
19. Akhmedova Shakhlo Malikovna// Age-Related Features of Changes in the Thymusgland in Children// Special Issue on COVID-19: Yesterday, Today, and Tomorrow//ISSN: 2660-4159 http://cajmns.centralasianstudies.org ppt 272-275
20. Sh. M. Axmedova*; D.B. Raxmatova. ANALYSIS OF THE DISTRIBUTION OF PODAGRIC NEPHROPATHY (COMMENT)// ANALYSIS OF THE DISTRIBUTION OF PODAGRIC NEPHROPATHY (COMMENT)// ACADEMICIA An International Multidisciplinary Research Journal// ISSN: 2249-7137 Vol. 11, Issue 1, January 2021 Impact Factor: SJIF 2021 = 7.492 // ppt 1668-1672 1515TRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES
21. Jurakulova Zebiniso Akhmatovna Current Issues of Infertility Diagnosis and Treatment in Women with Internal Genital Endometriosis// SYNERGY: JOURNAL OF ETHICS AND GOVERNANCE Volume: 01 Issue: 05 | 2021 ISSN: 2181-2616// ppt 67-74
22. Rizayeva M.A, Yahyoyeva H.Sh a common symptom of anemia in diabetic nephropathy …. Academicia: An International Multidisciplinary Research Journal 2021.— P. 1683-1686
23. Sh, Djuraeva A., and B. K. Badridinova. "METHODS FOR PREVENTING THE DEVELOPMENT OF TERMINAL RENAL FAILURE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS." British Medical Journal 2.1 (2022).
24. АСЛОНОВА Ш. Ж., БАДРИДИНОВА Б. К. ВЛИЯНИЕ МОКСОНИДИНА НА ОСНОВНЫЕ КОМПОНЕНТЫ МЕТАБОЛИЧЕСКОГО СИНДРОМА //Редколлегия журнала «Биология и интегративная медицина». – С. 86.
25. Kamalidinovna, B. B. (2022). Features of Phosphoric-Calcium Exchange in Patients Treated with Program Hemodialysis. Research Journal of Trauma and Disability Studies, 1(2), 39–45. Retrieved from http://journals.academiczone.net/index.php/rjtds/article/view/60
26. Dzhuraeva A. S., Badridinova B. K. ASSESSMENT OF THE INFLUENCE OF DYSLIPIDIMIA ON THE QUALITY OF LIFE OF PATIENTS RECEIVING PROGRAM HEMODIALYSIS //Art of Medicine. International Medical Scientific Journal. – 2022. – Т. 2. – №. 1.
27. Орзикулова Шахло Акмаловна. Ожирение И Гипертония Среди Мужчин 18-49 Летнего Возраста…..International Conference on Social and Humanitarian Research …2021—Р. 160
28. Nurilloeva Sh.N., Juraeva Kh.I. Adequacy pharmacotherapy of metabolic syndrome. // World journal of pharmaceutical research. August-Sept. - 2020. Volume 9. Issue 12. – P. 48 - 53.
29. Shodieva Nilufar Utkirzhonovna. Main risk factors for overweight and obesity in young people// Eurasian medical research Periodical/ Volume 7 ISSN: 2795-7624 ppt 141-144
30. Shodieva Nilufar Utkirzhonovna. Prevalence of the Main Risk Factors for Overweight and Obesity in Young People// Research journal of trauma and disability studies Volume 01 ISSN: 2720-6866 ppt 14-25
31. Shodieva Nilufar Utkirzhonovna. Basic risk factors for obesity in young adults annotation// ACADEMICIA: An International Multidisciplinary Research Journal / Volume 12 ISSN: 2249-7137// ppt 681-688
32. Nurilloeva Sh.N., Juraeva Kh.I. Adequacy pharmacotherapy of metabolic syndrome. // World journal of pharmaceutical research. August-Sept. - 2020. Volume 9. Issue 12. – P. 48 - 53.
33. Худоёрова Дилноза Ризоевна //ОЖИРЕНИЕ В КОНТЕКСТЕ ЭВОЛЮЦИОННОГО РАЗВИТИЯ СОВРЕМЕННЫЕ МЕТОДЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ.// Analytical Journal of Education and Development // Volume: 02 Issue: 10 | Oct-2022 PP 403-407 .sciencebox.uz
34. М.Ш. Тоиров, Ш.А. Орзиқулова. Таълим ва ривожланиш таҳлил. Анализ роли артериальной гипертонии и нарушений липидного обмена в развитии и прогрессировании хронической болезни почек у больных гипертонической Болезнью. Volume: 02 Issue: 10 |Oct- 2022 ISSN: 2181-2624 219-224 бетлар.
35. Ш.А. Орзиқулова. Таълим ва ривожланиш таҳлил. Факторы риска развития инфаркта миокарда у мужчин в различных возрастах. Vol. 2 No. 12 (2022), 206-212 бетлар
36. Tusunova Dilobar Erkinovna. MODERN UNDERSTANDING OF THE OCCURRENCE OF COGNITIVE IMPAIRMENTS IN ARTERIAL HYPERTENSION AND THEIR CORRECRION. Asian Journal of Pharmaceutical and Biological Research 2231-2218, Volume 10(Issue 3), 3–10.
Published
2023-12-06
How to Cite
Orzikulova, S. A. (2023). Clinical and Functional State of the Kidneys in Middle-Age Patients with Arterial Hypertension. Central Asian Journal of Medical and Natural Science, 4(6), 919-925. Retrieved from https://www.cajmns.centralasianstudies.org/index.php/CAJMNS/article/view/2152
Section
Articles
