Assessment of some biochemical and hematological parameters Children with hepatitis B and C

Waleed Abdulkhaleq Ahmed Al-Janabi; Raed shakir shnain; Ali abdl Husseen jawad; Nisreen Riyadh Mahdi Al_Musawi

Waleed Abdulkhaleq Ahmed Al-Janabi College of Medicine, University of Wasit, Iraq,
Raed shakir shnain aheed fayrooz hospital , Wasit Health Directorate, Iraqi Ministry of Health, Wasit, Iraq
Ali abdl Husseen jawad Al-Zahra Teaching Hospital, Wasit Health Directorate, Iraqi Ministry of Health, Wasit, Iraq
Nisreen Riyadh Mahdi Al_Musawi aheed fayrooz hospital , Wasit Health Directorate, Iraqi Ministry of Health, Wasit, Iraq

Keywords: hemoglobin (Hb), packed cell volume (PCV), and white blood cells (WBCs)

Abstract

The study showed that there is a noticeable difference in the average values of hemoglobin (Hb), packed cell volume (PCV), and white blood cells (WBCs) among children infected with hepatitis C compared to the control group. This distinction is statistically significant, with a p value of less than 0.01. However, when children with hepatitis B are compared with the control group, no significant difference is observed".

"Specifically, the results indicate that children with hepatitis C show a significant reduction in platelet count (PLT), with a p value of less than 0.01, while children with hepatitis B do not show a significant reduction in platelet count compared to controls. group. This suggests that hepatitis C has a direct effect on the PLT count, leading to a significant reduction, while hepatitis B does not"."The importance of these findings lies in the potential clinical implications for the diagnosis and monitoring of hepatitis C in children. The marked reduction in Hb counts, PCV, WBCs, and PLT in children with hepatitis C infection suggests that these parameters can serve as valuable indicators of disease progression and response to treatment. By monitoring these blood indicators, healthcare professionals can gain valuable insights into the effectiveness of interventions and adjust treatment plans accordingly".It is worth noting that the lack of a significant difference observed in children with hepatitis B compared to the control group does not mean that hepatitis B is less severe or less important. Each type of hepatitis presents unique challenges and potential complications, and further investigation is necessary to fully understand the impact of hepatitis B on blood markers and overall disease progression". In conclusion, the data in Figure 1 show a significant difference in the mean Hb, PCV, and WBC values of children with hepatitis C infection compared to the control group. In addition, a significant decrease in the number of PLT was observed in children with hepatitis C. In contrast, no significant difference was observed in children with hepatitis B compared to the control group". These findings underscore the importance of taking the specific type of hepatitis into account when analyzing blood parameters and highlight potential clinical implications for the diagnosis and monitoring of hepatitis C in children. Further research is warranted to fully understand the mechanisms and implications behind patient management.The results presented indicate a significant increase (P < 0.01) in the mean values of GPT, GOT, ALP, total bilirubin, direct bilirubin, and indirect bilirubin among female patients diagnosed with hepatitis B and hepatitis C when compared to Control group. These results indicate that liver function is significantly affected in female patients with these conditions.

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