INTESTINAL GIARDIASIS IN CHILDREN

Igamova Munavvar Abdullaevna

Igamova Munavvar Abdullaevna

Keywords: : giardia, diagnosis, methods, metronidazole.

Abstract

Giardiasis has a global distribution and it is a common cause of diarrhea in both children and adults and is transmitted via the fecal-oral route through direct or indirect ingestion of cysts. The laboratory diagnosis of Giardia spp. is mainly based on demonstration of microscopic cyst or trophozoite in stool samples but several immunological-based assays and molecular methods are also available for giardiasis diagnosis. The aim of this study was to conduct a review of the applied methods in medical laboratory and to highlight pitfalls and challenges of them for diagnosis of giardiasis. In this article we have evaluated the Giardia diagnostic methods with a broad review of literature, electronic databases and books. The search has covered the articles and some textbooks that have published up to 2018.

It has been concluded that traditional microscopy combination with stool concentration method should still be held in the routine medical laboratory due to economical and high sensitivity and immunological-based assay and molecular methods which are recommended to use as a complementary test to the traditional technique.

Giardiasis is highly prevalent in children and is often mildly symptomatic. First-line treatment is metronidazole, but treatment failure is not uncommon. We describe a paediatric series, to identify risk factors for treatment failure and to analyse the safety and effectiveness of other treatment strategies.

References

1. Igamova Munavvar Abdullaevna. (2023). GIARDIA LAMBLIA INFECTION: REVIEW OF CURRENT DIAGNOSTIC STRATEGIES FOR CHILDREN. Academia Science Repository, 4(06), 33–39. Retrieved from https://academiascience.com/index.php/repo/article/view/842
2. Keldiyorova, Z. D. (2021). Immunological features of infectious mononucleosis epstein-barr virus etiology in children. World medicine journal, (1), 1.
3. Keldiyorova, Z. D., Narzullaev, N. U., & Mirzoeva, M. R. (2022). Immunological disorders in infectious mononucleosis in children. Neuro Quantology. London, 20, 9600-9602.
4. Keldiyorova, Z. D., Ostonova, G. S., Mirzoeva, M. R., & Narzullaev, N. U. (2021). State of the immune system in children with infectious mononucleosis. New day in medicine. Бухоро-1 (33), 283-286.
5. Khamidova, N. K., Mirzoeva, M. R., & Narzullaev, N. U. (2021). Clinical and Immunological Study of the Effect of Different types of Therapy on the Course of Allergic Rhinitis in Children with Hymenolepiasis. Annals of the Romanian Society for Cell Biology, 1900-1908.
6. Khamidova, N. K., Mirzoeva, M. R., & Narzullaev, N. U. (2021). Clinical and Immunological Study of the Effect of Different types of Therapy on the Course of Allergic Rhinitis in Children with Hymenolepiasis. Annals of the Romanian Society for Cell Biology, 1900-1908.
7. Kosimovna, K. N. (2022). CLINICAL-EPIDCLINICAL-EPIDEMIOLOGICAL ASPECTS OF HYMENOLEPIDIOSIS IN PEDIATRIC AND EPIDEMIOLOGICAL ASPECTS OF HYMENOLEPIDIOSIS IN PEDIATRICS. INTERNATIONAL JOURNAL OF SOCIAL SCIENCE & INTERDISCIPLINARY RESEARCH ISSN: 2277-3630 Impact factor: 7.429, 11, 48-49.
8. Kosimovna, K. N. (2023). CLINICAL, NEUROLOGICAL AND IMMUNOLOGICAL PARAMETERS IN CHILDREN WITH HYMENOLEPIDOSIS AND PROTOZOAN INVASIONS. Galaxy International Interdisciplinary Research Journal, 11(4), 398-403.
9. Navruzova, U. O., Khamidova, N. Q., & Yusupov, S. H. (2019). A. Featurus of Periodontitis in Metabolo c Disorders. European journal of pharmaceutical and medical research, 3, 108-113.
10. Oblokulov, A. R., & Igamova, M. A. (2023). Optimization of Therapy Giardiasis.
11. Давыдова А. Н., Заячникова Т. Е., Шапошникова Н. Ф. Лямблиоз: Современные аспекты диагностики и лечения у детей. // Вестник ВОЛГМУ Выпуск 1 (53). 2015. С.133-135.
12. Игамова М.А. (2023). Гижжа инвазияси бўлган болаларда микроэлемент дисбалансининг намоён бўлишининг хусусиятлари тениаринхоз ташҳисланган турли ёшдаги пациентларда иммун ва цитокин ҳолатининг тавсифи // Тиббиётда янги кун -2023.-9(59)-P.265-270
13. Игамова М.А., Облокулов А.Р. (2023). Тениаринхоз ташҳисланган турли ёшдаги беморларда иммун ва цитокин статуси тавсифи // Тиббиётда янги кун -2023.-6(56)-P.346-351
14. Игамова М.А., Облокулов А.Р., Иброхимова Ҳ.Р.(2023). Тениаринхоз ташҳисланган турли ёшдаги беморларда иммун ва цитокин статусига тавсифи // Тиббиётда янги кун -2023.-5(55)-P.613-618
15. Келдиёрова, З. Д. (2021). Иммунологические особенности инфекционного мононуклеоза эпштейна-барр-вирусной этиологии у детей. Новый день в медицине. Бухоро, 2, 34.
16. Келдиёрова, З. Д. (2023). Оценка Клеточного Лимфоцитарного Иммунитета При Инфекционном Мононуклеозе Эпштейна-Барр-Вирусной Этиологии У Взрослых. Central Asian Journal of Medical and Natural Science, 4(5), 399-407.
17. Келдиёрова, З. Д. НОВЫЙ ДЕНЬ В МЕДИЦИНЕ. НОВЫЙ ДЕНЬ В МЕДИЦИНЕ Учредители: Бухарский государственный медицинский институт, ООО" Новый день в медицине", (2), 231-234.
18. Кучеря Т.В., Макарова Т.А., Кочергина Е.А., Авдюхина Т.И. Лечение лямблиоза у детей в современных условиях: эффективность и выбор специфического препарата // Медицинская паразитология и паразитарные болезни. –2002. –№ 3. – С. 33-35.
19. Хамидова, Н. К. (2021). Клинико-иммунологические показатели гименолепидоза с аллергическом ринитом у детей в зависимости от вида терапии. Central Asian Journal of Medical and Natural Science, 331-333.
20. Хамидова, Н. К. (2023). ГИМЕНОЛЕПИДОЗ БИЛАН КАСАЛЛАНГАНГАН БОЛАЛАРДА КЛИНИК-ИММУНОЛОГИК КЎРСАТКИЧЛАР. Биология, (3), 144.
21. Хамидова, Н. К. (2023). Клинико-Иммунологическая Характеристика Детей С Гименолепидозом В Бухаре. AMALIY VA TIBBIYOT FANLARI ILMIY JURNALI, 2(10), 71-76.