Morphometric Indices of Tissue Structures During Periods  of Safe Prostatic Hyperplasia

Khamrayev Obidjon  Ashurmamatovich

Khamrayev Obidjon Ashurmamatovich Andijan State Medical Institute, Department of Pathological Anatomy and Forensic Medicine

Keywords: prostate gland, hyperplasia, glandular epithelium, fibrous tissue, inflammatory infiltrate

Abstract

this article calculates and analyzes morphometric indices of tissue structures during the periods of malignant prostatic hyperplasia development. As material, morphometric calculations of biopsies from patients diagnosed with safe prostatic hyperplasia were performed. In safe prostatic hyperplasia, there was a dramatic increase in the parenchymatous glandular structures in the gland tissue and the area occupied by the glandular epithelium therein, according to the periods of the disease. It was found that the area of fibrous tissue in the stroma was increased and the area of smooth muscle cells and inflammatory infiltrate was decreased, monandically increasing the hyperplasia of the glandular epithelium and expanding the area. It was observed that by the 3rd period of the disease, the area occupied by smooth muscle cells decreased by 1.7 times compared to the 1st period, and the area of inflammatory infiltrate decreased by 2 times.

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